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Single-dose Zika vaccine works in animals – study

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by AFP

Paris – An innovative vaccine made from genetic material protected lab animals from the Zika virus in experiments, scientists reported Thursday, calling it a ‘’promising’’ lead in fighting the threat to humans.

A single, low dose of the vaccine shielded mice exposed to Zika five months after the shot, they reported in the journal Nature.

Monkeys exposed five weeks after they were innoculated were also not affected by the virus.

“We observed rapid and durable protective immunity without adverse events,’’ said senior author Drew Weissman, a professor at the University of Pennsylvania School of Medicine.

“This candidate vaccine represents a promising strategy for the global fight against Zika virus.’’

Since Zika erupted on a large scale in mid-2015, more than 1.5 million people have been infected, mostly in Brazil and other countries in South America.

It is transmitted mainly by mosquitoes, but also through sex.

While the virus causes mild, flu-like symptoms in most people, pregnant women run the risk of giving birth to babies with severe brain damage.

The World Health Organization declared a global health emergency in February last year, and declared it over in mid-November.

Several vaccines for Zika are under development, and a few are in the early phases of human trials.  Most vaccines are made from weakened or inert versions of the targeted virus, and seek to trigger a build-up of antibodies to project against full-strength, live virus.

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